Senior Scientist, In Vitro Biology Job at Planet Group, San Diego, CA

eW8rRzU4S2RWV0dWVmRNMnQ4Vkh4N3FJRFE9PQ==
  • Planet Group
  • San Diego, CA

Job Description

Senior Scientist, In Vitro Biology
The Senior Scientist, In Vitro Biology is a laboratory-based position conducting research and experiments supporting drug discovery research. This person will work with minimal supervision in a cross-disciplinary team to develop and/or optimize biochemical in-vitro and cell-based assays. They are expected to bring broad breadth of knowledge from hands-on experience in an industrial setting and maintain a high level of cutting-edge technical expertise to recommend and implement novel and enabling technologies to meet specific project needs.

Responsibilities:
  • Work primarily at the bench developing novel assays to assess potency of inhibition of enzymes, protein-protein or protein-ligand interactions.
  • Work closely with adjacent functional teams to optimize and validate new assays for transfer to the in vitro screening team or to external CROs.
  • Provide mentorship and technical guidance to the in vitro pharmacology team in troubleshooting and improving assay performance.
  • Propose and conduct experiments to characterize mode of action for inhibitors, including enzyme or protein binding kinetics and deconvoluting targets in complex pathways.
  • Draw on knowledge of cutting-edge assay technologies to recommend and implement fit-for-purpose solutions to address scientific needs.
  • Prepare research presentations and present findings at team meetings and for scientific leadership.
Requirements
  • B.S. degree with 10+ years biotech/pharma industry experience or Ph.D. degree in Biochemistry, Biophysics, Molecular Biology, Cell Biology, or a related field with 5+ years industrial experience is required.
  • The candidate must have proven experience performing assay development and optimization for inhibitor screening in an industrial setting.
  • Hands-on experience with development and execution of diverse plate-based assays for mid- to high-throughput screens is essential.
  • Previous hands-on experience designing experiments to characterize inhibitor mechanisms of action and binding kinetics.
  • A background in automation, cell culture, or protein binding assays (e.g., AlphaLISA, FP, HTRF, CETSA, BRET, etc) is a plus.
  • Strong troubleshooting and problem-solving skills and enthusiasm for exploring new assay technologies.
  • Must be able to work independently with supervision and take guidance from multiple stakeholders in a matrix environment.
  • Adaptable/flexible with a teamwork-oriented attitude and excellent interpersonal and organizational skills: willing and able to multitask and adjust to shifting priorities in a collaborative, fast-paced environment.
  • Excellent written and oral communication skills for effective presentation of complex scientific data to cross-functional teams and senior level scientists.
  • Knowledge of computer software and Microsoft applications (Word, Excel, PowerPoint, GraphPad Prism).

Job Tags

Contract work, Flexible hours, Shift work,

Similar Jobs

WS Development

Senior Manager, Accounting Job at WS Development

 ...Overview Responsible for management and oversite of the companys property accounting functions including assisting with establishing and maintaining accounting principles, practices, procedures, initiatives and industry best practices. Review financial reports and... 

Small Potato Trucking

SWIFT WALMART MOBERLY CDL-A REGIONAL DRIVER Job at Small Potato Trucking

We are looking for professional and committed drivers. Teams, trainees and solo drivers for Reefer trailers Home once a week with a night shift. Weekends and holidays are workdays except Christmas and Thanksgiving. Pay $1,400.00 ($0.49 to $061 cpm) with 2,1...

PRO LC GROUP

Remote Task Support Specialist Job at PRO LC GROUP

 ...entry, and documentation Assist with scheduling, internal coordination, and...  ...Benefits Perks: Flexible work schedule Growth and development support...  ...support Employee discounts Work-from-home flexibility Supportive team environment... 

Spartanburg County

Commercial Appraiser Job at Spartanburg County

Under the general supervision of the Chief Commercial Appraiser performs difficult technical work appraising for assessment and tax purposes. Appraises commercial, residential, farm and undeveloped real estate. Maintains records and files; prepares reports. Must have... 

Boston Medical Center

Neuropsychologist (PhD, PsyD) Job at Boston Medical Center

Monday through Friday 8am-4pm Boston Medical Center Brighton Outpatient Psychiatry. Duties and Responsibilities Conduct comprehensive neurodevelopmental and/or neurocognitive evaluation assessing intellectual, neuropsychological, and emotional behavioral...